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From the picture bank

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Resonance Light Scattering Technology Increases Sensitivity

2002-08-04 admin
miro4.jpg

Genicon Sciences today announced it has launched its first commercially available nano-based product -- an ultra-sensitive signal generation and detection system for microarrays and other assays -- capable of deriving more data from smaller amounts of biological
material and detecting genes that are expressed at very low levels and are critical to drug discovery, proteomics, genomics and clinical
diagnostics.

Genicon Sciences' proprietary Resonance Light Scattering (RLS) non-fluorescent technology, the basis for the One-Color Microarray
Toolkit launched today, is up to 1 million times more sensitive than current methods used for detecting biological interactions. As a
result, researchers can conduct up to 1,000 more experiments from the same amount of biological material.

The One-Color Microarray Toolkit is part of a fully integrated detection system providing researchers with a total assay platform for
gene expression.

This system is available through Genicon Sciences' distribution partner, QIAGEN, as the HiLight Array Detection System and includes Genicon
Sciences' GSD-501 RLS Detection and Imaging Instrument and ArrayVision RLS image analysis software.

"Our goal is to provide open access to our ultra-sensitive RLS technology products in an easy-to-use, integrated system available for
the entire life science research community" said Patrick J. Mallon, president and CEO for Genicon Sciences.

"We're very happy to see our business model implemented and reach the commercialization stage."

Genicon Sciences' RLS-based signal generation and detection system has been tested at such prominent research institutions and microarray core facilities as the Centers for Disease Control, the City of Hope
Medical Center, the U.S. Food and Drug Administration, The University of Michigan, and The University of Pittsburgh.

RLS technology is based on the physical properties of nano-sized metallic particles called RLS Particles.

The characteristics of these RLS Particles, including their size, shape and composition,
cause them to scatter light when illuminated so that the specific levels of intensity and differing colors emitted can be easily detected, differentiated and quantified.

As a result, attaching RLS
Particles to specific biological content enables analytes to be
detected and measured with greater sensitivity and accuracy than existing commercially available assay systems.

The One-Color Microarray Toolkit is designed for the detection of nucleic acids and is the first commercial release from Genicon Sciences' portfolio of assay products, services and solutions
currently under development. Future products will enable users to perform bioassays for proteins, genes, cells and their components, and small and large molecule drugs.



www.qiagen.com.
www.geniconsciences.com.


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Comments

Mon, 04/07/2008 - 20:04 — graham28

This is all very

This is all very interesting, I am looking forward to learn about new applications of this Toolkit. Medical research makes important progresses and it's easy to predict now that many things will change for the better specially in the genetic field.Technology Transfer opportunities could easily enhance this process.


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